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Longevity and Anti-Aging

Beta-glucan (β-glucan) is a dietary fiber that may support healthier aging by helping the gut produce protective metabolites and reducing inflammatory stress signals, but most evidence comes from animal studies and the size of benefit in people remains uncertain.

    Written by:
    1. Beta Glucan PhD Team,

      Beta Glucan PhD Team

      Beta Glucan PhD Team

    We analyze peer-reviewed research on supplements.

    We rely on peer-reviewed scientific research to determine what’s truly effective. Our goal is to provide clear, unbiased information to help you make better health decisions.

    We use AI tools to help summarize studies, and every piece of content is reviewed and approved by qualified experts, ensuring it’s accurate and trustworthy.

    Beta Glucan is fully independent — we don’t sell products, run ads, or accept sponsorships. Our only focus is delivering reliable, science-backed insights.

    Podcast

    Retraining The Aging Immune System

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    Daily fiber drinks did not stop a painkiller-related “leaky gut” effect in older adults after 6 weeks. New

    “Refined” lab diets sped up aging-like problems in mouse liver and brain; adding fiber slowed memory decline but didn’t fix liver issues. New

    Barley-fiber–rich extracts eased “fatty-diet + stress” memory problems in mice by improving gut microbes, gut lining, and brain signals. New

    Treating gum disease with a yeast-fiber supplement protected aging rats’ heart arteries from “lining” damageNew

    Yeast fiber reshaped the gut, calmed brain inflammation, and eased Alzheimer-like changes in high-fat-fed rats. New

    1. Kromm Aging-related decline in the liver and brain is accelerated by refined diet consumption 2025
    2. Mo Yeast β-glucan alleviates high-fat diet-induced Alzheimer's disease-like pathologies in rats via the gut-brain axis 2024
    3. Fan Barley polysaccharides modulate metabolic and mild cognitive impairment in naturally aging mice through the liver-gut-brain axis 2025
    4. Mall Effects of Dietary Fibres on Acute Indomethacin-Induced Intestinal Hyperpermeability in the Elderly: A Randomised Placebo Controlled Parallel Clinical Trial 2020
    5. Huang Oat β-glucan enhances gut barrier function and maintains intestinal homeostasis in naturally aging mice 2025
    6. Silva Experimental Periodontal Disease Triggers Coronary Endothelial Dysfunction in Middle-Aged Rats: Preventive Effect of a Prebiotic β-Glucan 2021

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