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Infectious Disease

From pneumonia to sepsis, infections remain a leading cause of illness and death worldwide. Beta glucan, a natural immune-modulating fiber, has been studied for decades as a way to strengthen frontline defenses and improve recovery from bacterial, viral, fungal, and parasitic infections.

We analyze peer-reviewed research on supplements.

We rely on peer-reviewed scientific research to determine what’s truly effective. Our goal is to provide clear, unbiased information to help you make better health decisions.

We use AI tools to help summarize studies, and every piece of content is reviewed and approved by qualified experts, ensuring it’s accurate and trustworthy.

Beta Glucan is fully independent — we don’t sell products, run ads, or accept sponsorships. Our only focus is delivering reliable, science-backed insights.

Podcast

Beta Glucans: The Universal Biological Key to Supercharging Immunity

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A beta-glucan plus selenium and zinc supplement improved micronutrient status and showed non-significant immune-response trends after influenza or COVID-19 vaccination.New

Beta-glucan (β-glucan) Derived from Shiitake Mushrooms may Reduce COVID Immune Response linked to Lung Injury New

Yeast Beta-glucan (β-glucan) Supplements Show Promise in Reducing Severe Inflammation and Clotting Risks in COVID-19 PatientsNew

An Alpha-glucan (⍺-glucan) Supplement Shows Promise for Easing Chronic Symptoms and Inflammation in Lyme Disease PatientsNew

An Oral Beta-glucan (β-glucan) Supplement reduces the severity of Lyme Arthritis and Boosts Cellular Immune Response in MiceNew

Yeast Beta Glucan (β-glucan) Optimizes the Immune Response to Prevent Lung Damage During Flu Infection in MiceNew

A Yeast Beta Glucan (β-glucan) Capsule Supplement Reduces the Severity of Cold Symptoms in Immunocompromised AdultsNew

A Daily Beta Glucan (β-glucan) Supplement May Boost Flu Shot Benefits in Older AdultsNew

Beta Glucan (β-glucan) Enhances Antibody Response Following Flu Vaccination in Older AdultsNew

A β-glucan Drink Supplement Reduces the Severity of Cold Symptoms in Marathon Runners New

  1. Mah Beverage Containing Dispersible Yeast β-Glucan Decreases Cold/Flu Symptomatic Days After Intense Exercise: A Randomized Controlled Trial 2020
  2. Moreno Yeast Beta-Glucan Enhances Antibody Response Following Influenza Vaccination - A Double-Blind, Randomized, Placebo-Controlled Pilot Trial. 2025
  3. Dharsono Effects of Yeast (1,3)-(1,6)-Beta-Glucan on Severity of Upper Respiratory Tract Infections: A Double-Blind, Randomized, Placebo-Controlled Study in Healthy Subjects 2019
  4. Khan β-Glucan reprograms neutrophils to promote disease tolerance against influenza A virus 2025
  5. Salerno A Pilot Open-Label Study Assessing the Effects of AHCC Supplementation on Lyme Disease Patients 2019
  6. Raghavan Beneficial effects of novel aureobasidium pullulans strains produced beta-1,3-1,6 glucans on interleukin-6 and D-dimer levels in COVID-19 patients; results of a randomized multiple-arm pilot clinical study 2021
  7. Murphy β-Glucan extracts from the same edible shiitake mushroom Lentinus edodes produce differential in-vitro immunomodulatory and pulmonary cytoprotective effects - Implications for coronavirus disease (COVID-19) immunotherapies. 2020
  8. Rodriguez Effect and Tolerability of a Nutritional Supplement Based on a Synergistic Combination of β-Glucans and Selenium- and Zinc-Enriched Saccharomyces cerevisiae (ABB C1®) 2021
  9. Nakayama Immunogenicity, safety, and tolerability of a β-glucan-CpG-adjuvanted respiratory syncytial virus vaccine in Japanese healthy participants aged 60 to 80 years: A phase 2, randomized, double-blind, dose-finding study 2025
  10. Panão-Costa Yeast-Derived Glucan Particles: Biocompatibility, Efficacy, and Immunomodulatory Potential as Adjuvants and Delivery Systems 2025
  11. Kournikakis Anthrax-Protective Effects of Yeast Beta 1,3 Glucans 2003
  12. McFarlin Baker's yeast beta glucan supplementation was associated with an improved innate immune mRNA expression response after exercise 2024
  13. Sato Curdlan, a Microbial β-Glucan, Has Contrasting Effects on Autoimmune and Viral Models of Multiple Sclerosis 2022
  14. Evans Effect of a Euglena gracilis Fermentate on Immune Function in Healthy, Active Adults: A Randomized, Double-Blind, Placebo-Controlled Trial 2019
  15. Adams β-Glucan Protects Against Sepsis-Induced Kupffer Cell Loss by Inhibiting Pyroptosis and Promoting Self-Renewal 2025
  16. Dos Santos β-Glucan-Induced Trained Immunity Protects against Leishmania braziliensis Infection: A Crucial Role for IL-32 2019
  17. Prevel β-Glucan reprograms alveolar macrophages via neutrophil/IFNγ axis in a murine model of lung injury 2025

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