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COVID

Beta-glucans(β-glucans), recognized as biological-response modifiers derived from sources like edible mushrooms or black yeast, exhibit promising potential as adjunct agents in the management of COVID-19 by reducing key inflammation markers like IL-6 and coagulopathy  markers like D-dimer, which are associated with severe disease and mortality. [1][8][10]

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Beyond Antibodies: How Beta Glucans Could Train Your Immune System

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Chewable mushroom β-glucan (with vitamin D and zinc) cut kids’ colds and other respiratory infections by about 15% over three months.New

A beta-glucan plus selenium and zinc supplement improved micronutrient status and showed non-significant immune-response trends after influenza or COVID-19 vaccination.New

Beta-glucan (β-glucan) Derived from Shiitake Mushrooms may Reduce COVID Immune Response linked to Lung Injury New

Yeast Beta-glucan (β-glucan) Supplements Show Promise in Reducing Severe Inflammation and Clotting Risks in COVID-19 PatientsNew

  1. Raghavan Beneficial effects of novel aureobasidium pullulans strains produced beta-1,3-1,6 glucans on interleukin-6 and D-dimer levels in COVID-19 patients; results of a randomized multiple-arm pilot clinical study 2021
  2. Rodriguez Effect and Tolerability of a Nutritional Supplement Based on a Synergistic Combination of β-Glucans and Selenium- and Zinc-Enriched Saccharomyces cerevisiae (ABB C1®) 2021
  3. Murphy β-Glucan extracts from the same edible shiitake mushroom Lentinus edodes produce differential in-vitro immunomodulatory and pulmonary cytoprotective effects - Implications for coronavirus disease (COVID-19) immunotherapies. 2020
  4. Anne Geller 1 2,Jun Yan 2 Could the Induction of Trained Immunity by β-Glucan Serve as a Defense Against COVID-19? 2020
  5. Ikewaki Antibody dependent disease enhancement (ADE) after COVID-19 vaccination and beta glucans as a safer strategy in management 2023
  6. Ikewaki β-glucans: wide-spectrum immune-balancing food-supplement-based enteric (β-WIFE) vaccine adjuvant approach to COVID-19. 2021
  7. Mallakpour Chitosan, alginate, hyaluronic acid, gums, and β-glucan as potent adjuvants and vaccine delivery systems for viral threats including SARS-CoV-2: A review. 2021
  8. Mirończuk-Chodakowska Beta-Glucans from Fungi: Biological and Health-Promoting Potential in the COVID-19 Pandemic Era. 2021
  9. Ikewaki Controlled modulation of all the arms of the immunity including innate immunity by biological response modifier glucans, a simple yet potential nutritional supplement strategy to fight COVID-19. 2022
  10. Preethy Beneficial Immune Regulation by Biological Response Modifier Glucans in COVID-19 and Their Envisaged Potentials in the Management of Sepsis 2022
  11. Jesenak Novel Chewable Pleuran-Based Supplement Decreases Respiratory Tract Infections in Children: A Randomised Controlled Trial 2025

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