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Arthritis

Arthritis is driven by chronic inflammation and immune imbalance. Beta glucans, natural polysaccharides found in yeast, fungi, and plants, show promise in regulating immune pathways and reducing oxidative stress that drive joint damage.

We analyze peer-reviewed research on supplements.

We rely on peer-reviewed scientific research to determine what’s truly effective. Our goal is to provide clear, unbiased information to help you make better health decisions.

We use AI tools to help summarize studies, and every piece of content is reviewed and approved by qualified experts, ensuring it’s accurate and trustworthy.

Beta Glucan is fully independent — we don’t sell products, run ads, or accept sponsorships. Our only focus is delivering reliable, science-backed insights.

Podcast

Beta Glucans & Arthritis

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A one-time β-glucan “memory” signal, driven by a switch called MITF, can push certain immune cells to chew up more bone during gum disease and arthritis.New

Mushroom-derived β-glucan eased arthritis in mice by calming joint inflammation and nudging gut bacteria toward a healthier balance.New

Certain yeast-type sugars (β-glucans) calmed psoriasis-like and arthritis-like disease in mice by working through a macrophage receptor.New

A β-glucan trigger caused “dry mouth” in a mouse model by prompting antibodies that block saliva-making signals.New

An Alpha-glucan (⍺-glucan) Supplement Shows Promise for Easing Chronic Symptoms and Inflammation in Lyme Disease PatientsNew

An Oral Beta-glucan (β-glucan) Supplement reduces the severity of Lyme Arthritis and Boosts Cellular Immune Response in MiceNew

  1. Vetvicka Glucan Supplementation Ameliorates Some Health Problems Related to the Development of Lyme disease 2019
  2. Salerno A Pilot Open-Label Study Assessing the Effects of AHCC Supplementation on Lyme Disease Patients 2019
  3. Choi Autoantibody-Mediated Dysfunction of Salivary Glands Leads to Xerostomia in SKG Mice 2019
  4. Fahlquist-Hagert Variants of beta-glucan polysaccharides downregulate autoimmune inflammation 2022
  5. Zheng Polyporus Umbellatus polysaccharide ameliorates rheumatoid arthritis via inhibiting inflammation and regulating gut microbiota 2025
  6. Haacke Innate immune training of osteoclastogenesis promotes inflammatory bone loss in mice 2025

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